«I had the privilege to work with Carlos during our Master’s in pharmacology. Carlos is an outstanding professional in the field of pharmaceutical industry with deep knowledge in drug development from discovery to market. Carlos is a dedicated and high skilled R&D professional, with a huge scientific background as well as valuable soft skills that makes him a key person for the good project development and success of the team.»
Acerca de
Experiencia y educación
Licencias y certificaciones
Experiencia de voluntariado
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Teaching Assistant
Harvard T.H. Chan School of Public Health Center for Executive and Continuing Professional Education
- actualidad 5 años 3 meses
Salud
Assignment and exam corrections, forum posts validation and grading, ing students.
Publicaciones
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Therapeutic action and underlying mechanisms of a combination of two pentacyclic triterpenes, alpha- and beta-amyrin, in a mouse model of colitis
British Journal of Pharmacology
alpha- and beta-amyrin are pentacyclic triterpenes found in plants and are known to exhibit pronounced anti-inflammatory effects. Here, we evaluated the effects of a 1:1 mixture of alpha- and beta-amyrin (alpha,beta-amyrin) on an experimental model of colitis in mice
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Synthesis and pharmacological activity of chalcones derived from 2,4,6-trimethoxyacetophenone in RAW 264.7 cells stimulated by LPS: quantitative structure-activity relationships
Bioorganic Medicinal Chemistry Journal
Inhibition of nitric oxide (NO) production by altering the expression of induced enzymes involved is potentially an important strategy for obtaining antiinflammatory agents. In the search for hits to obtain lead compounds for new drugs of this class, 14 synthetic chalcones derived from 2,4,6-trimethoxyacetophenone were evaluated in of their inhibitory action, in vitro, in relation to NO production in murine macrophages of the line RAW 264.7 induced by bacterial lipopolysaccharides (LPS).
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Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw
British Journal of Pharmacology
alpha-Humulene and trans-caryophyllene are sesquiterpene compounds identified in the essential oil of Cordia verbenacea which display topical and systemic anti-inflammatory effects in different experimental models. However, the molecular mechanisms through which they exert their anti-inflammatory activity still remain unclear. Here, we evaluate the effects of alpha-humulene and trans-caryophyllene on the acute inflammatory responses elicited by LPS.
Patentes
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EXTRATOS DE PLANTA ENRIQUECIDOS COM DERIVADOS DE IPOLAMIDA COMO IMUNOSSUPRESSORES PARA TRATAMENTO DE TRANSTORNOS IMUNOLÓGICOS
Presentada el BR BR 11 2019 017128 2
The invention describes extracts from plants of the genus Stachytarpheta enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders. The isolated active compounds and a process of producing these are also disclosed.
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PLANT EXTRACTS ENRICHED WITH IPOLAMIIDE DERIVATIVES AS IMMUNOSUPPRESSANTS FOR TREATING IMMUNOLOGICAL DISORDERS
Presentada el US US20200231561
The invention describes extracts from plants of the genus Stachytarpheta enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders. The isolated active compounds and a process of producing these are also disclosed.
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COMPOSTOS, PROCESSO DE PRODUÇÃO DE COMPOSTOS, EXTRATO ENRIQUECIDO, FRAÇÕES ATIVAS DE EXTRATO ENRIQUECIDO, PROCESSO DE PRODUÇÃO DE EXTRATO ENRIQUECIDO, MÉTODO DE SELEÇÃO DE BIOMASSA VEGETAL PARA PRODUÇÃO DE EXTRATO ENRIQUECIDO, COMPOSIÇÃO E USO PARA TRAT.
Presentada el BR BR 10 2017 003318 0
The invention describes extracts from plants of the genus Stachytarpheta enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders. The isolated active compounds and a process of producing these are also disclosed.
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PLANT EXTRACTS ENRICHED WITH IPOLAMIIDE DERIVATIVES AS IMMUNOSUPPRESSANTS FOR TREATING IMMUNOLOGICAL DISORDERS
Presentada el BR EP3583103
The invention describes extracts from plants of the genus Stachytarpheta enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders. The isolated active compounds and a process of producing these are also disclosed.
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Composições antidiarreicas e antimicrobianas para tratamento de diarreia de origem inflamatória ou causada por microorganismos
Expedida BR PI0802674-2
Proyectos
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ANÁLISE DA UTILIZAÇÃO DO TECHNOLOGY ROAPPING E SUA IMPORTÂNCIA PARA A GESTÃO ESTRATÉGICA DE PORTFÓLIO DE PROJETOS DE INOVAÇÃO
Reconocimientos y premios
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2020 Outstanding Teaching Assistant
Harvard T.H. Chan School of Public Health
PPCR Program recognizes TAs who have demonstrated an extraordinary performance on the course by extending this award.
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Clinical Research Scholar Award
Harvard T.H. Chan School of Public Health
Award given in recognition of outstanding performance and participation in the Principles and Practice of Clinical Research 2019.
Idiomas
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English
Competencia básica profesional
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Portuguese
Competencia bilingüe o nativa
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German
Competencia básica
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